Brachyury gene Essay Example | Topics and Well Written Essays - 250 words

Brachyury gene - Essay ExampleThe nature of Brachury proteins explain the gut and posterior mesoderm characteristics of the farming animalia (Evans et al. 2012) that is, homogenous and heterogeneous animals. In cases where the Brachyury proteins fail to express themselves in the gut and posterior mesoderm, it means that those animals lost these T domain genes in the subprogram of evolution. Brachyury proteins of the T domain are found in ascidians, cephalochordates, and hemichordates. Since they belong to the T domain, this gives DNA binding characteristic to the Brachyury proteins. According to Beddington, Rashbass and Wilson (1992 159), the nature of the well known swipe mutant, Brachyury (T) in cloned mouse is revealed by its season, which is an open reading frame of 436 amino acids. In the blastocyst stage embryo, this T gene is present in the intimate cell mass, which is then followed by the primordial stripe. Brachyury proteins can also be considered as transcriptional act ivators, because they have the ability to get attached to a 24-bp palindromic target sequence (Brody 1997, par. 24).Beddington, R.S.P., Rashbass, P., & Wilson, V., 1992. Brachyury - a gene affecting mouse gastrulation and early organogenesis. Devclopmcni 1992 Supplement. Online Available at Accessed 20 April 2013Evans, A.L., Faial, T., Gilchrist, M.J., Down, T., Vallier, L., et al., 2012. Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells. PLoS ONE, vol.7, no.3, p. e33346. Online Available at Accessed 19 April